Pathophysiology of hemolysis in infections with Hemophilus influenzae type b.

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چکیده

منابع مشابه

Pathophysiology of hemolysis in infections with Hemophilus influenzae type b.

The capsular polysaccharide of Hemophilus influenzae type b, polyribosyl ribitol phosphate (PRP), is released from growing organisms during human infection and can be found in body fluids. It binds to untreated erythrocytes. Many patients with invasive infections with this organism develop significant hemolysis, but the mechanism has been unclear. We have found that PRP binds to human erythrocy...

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Hemophilus influenzae type b pneumonia.

SUMMARY Thirteen patients with Haemophilus influenzae type b pneumonia are reported to emphasise the clinical, radiographic, and therapeutic aspects of this illness. All but one patient was tnder 21 years of age. The presenting complaint was a variable duration of upper respiratory infection and fever in most cases. One-third of patients had radiographic evidence of pleural involvement ; one-th...

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Hemophilus influenzae type B cellulitis in adults.

Cellulitis due to Hemophilus influenzae type B is a rare but treatable event in adults. Herein is described a 67-year-old woman with anterior neck cellulitis caused by H. influenzae type B, documented by positive blood culture results. Six additional cases reported in the literature are reviewed. The following clinical syndrome emerges: the patient is usually older than 50 years of age, and pha...

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MODE OF ACTION OF STREPTOMYCIN ON TYPE b HEMOPHILUS INFLUENZAE

In all of ten strains of H. influenzae examined prior to exposure to streptomycin a very small fraction of the bacteria formed colonies in the presence of 1,000 units of streptomycin per cc. These variant organisms possess the characteristics of bacterial mutants. 1. Different independent cultures of the same strain on different occasions, and even cultures seeded in a single test with the same...

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Haemophilus influenzae type b infections in adults.

31 cases of invasive Haemophilus influenzae type b infections occurred in adults in Denmark during a period of 2 years and 5 months corresponding to an incidence of 0.3/100,000/year. Only 6 patients had no underlying condition. The incidence of H. influenzae type b infections in adults will probably rise in the future, because the increasing use of therapeutic measures affecting the immune syst...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1986

ISSN: 0021-9738

DOI: 10.1172/jci112439