Pathophysiology and diagnosis of disseminated intravascular coagulation

Disseminated intravascular coagulation: pathophysiology and principles of management.

DIC is a thrombohemorrhagic syndrome which occurs in association with well-defined clinical disorders such as septicemia, acute leukemia, snake envenomation, hypoxic states, etc. These disease conditions trigger the coagulation cascade in vivo resulting in formation of microthrombi, activation of fibrinolysis and a bleeding tendency. The important and most frequently observed laboratory abberra...

Disseminated intravascular coagulation= رثختلا لخادرشتنملا ةيعوألا DISSEMINATED INTRAVASCULAR COAGULATION

Recent acquisitions in the pathophysiology, diagnosis and treatment of disseminated intravascular coagulation

Disseminated intravascular coagulation (DIC) is a disorder characterized by both acute generalized, widespread activation of coagulation, which results in thrombotic complications due to the intravascular formation of fibrin, and diffuse hemorrhages, due to the consumption of platelets and coagulation factors. Systemic activation of coagulation may occur in a variety of disorders, including sep...

Disseminated Intravascular Coagulation

EVIDENCE DEFINITIONS  Class I: Prospective randomized controlled trial.  Class II: Prospective clinical study or retrospective analysis of reliable data. Includes observational, cohort, prevalence, or case control studies.  Class III: Retrospective study. Includes database or registry reviews, large series of case reports, expert opinion.  Technology assessment: A technology study which doe...

Disseminated intravascular coagulation.

OBJECTIVES To provide an overview of the pathophysiology, manifestations, diagnosis, and treatment of disseminated intravascular coagulation (DIC) as it occurs in cancer. DATA SOURCES Published articles, research reports, and book chapters. CONCLUSIONS The syndrome of DIC is a serious hypercoagulation state that in its acute form may be life-threatening. The hemorrhage and intravascular coa...