Pathophysiological aspects of renal stone formation and stone types
نویسندگان
چکیده
Urinary stone formation is one of the oldest and most widespread diseases known to man. The disease has a multifactorial etiology that includes anatomic, environmental, genetic, infectious, metabolic, nutritional, importantly socio-economic factors. It caused by biochemical imbalance in urine between stone-forming inhibitors promotors process as lithogenesis. mechanisms underlying development urinary stones are not fully understood, but it can be said they generally begin increased supersaturation lithiasis promoters urine, followed nucleation aggregation. Subsequently, crystals combine with other solution form agglomerates accumulate kidney. Free radical-mediated oxalate-induced renal membrane damage promotes crystal retention at surface papilla, well lower levels. In addition, type identification great interest guiding physician an effective diagnosis, which allows determine causes order treat prevent recurrence. this context, present study reviews current knowledge on pathophysiological aspects kidney stones.
منابع مشابه
Stone Composition in Patients Who Undergo Renal Stone Surgery: Review of 423 Stone Analyses in Southern Iran
متن کامل
Stone Formation
1. Urinary stones 1.1 Pathogenesis 1.2 Classification of stones 1.2.1 Calcium stones 1.2.2 Uric Acid Stones 1.2.3 Magnesium Ammonium Phosphate Stones, struvite or infection stones 1.2.4 Cystine 1.3 Risk factors 1.3.1 Non-genetic factors 1.3.1.1 Diet 1.3.1.2 Body size 1.3.1.3 Environment 1.3.2 Genetic factors 2. Other urological stones: Testicular microlithiasis 3. Biliary and gallbladder stones...
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Studies on the pathogenesis of urolithiasis have mainly focused on metabolic disorders. However, metabolic disorders alone are not sufficient to explain the problem. In the present study, morphological and urodynamic differences of the upper urinary tract on both the stone and normal side were examined. There were 35 cases of those who had experienced unilateral, recurrent, and/or multiple ston...
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The intake of minerals are very important in maintaining health, but in returning to health either. Mineral waters represents a source of minerals with high bioavailability. There are evidence based studies for the efficency of mineral waters in a series of disorders for both internal and external cures. The advantage of mineral waters in renal lithiasis are significant and the risks of stone f...
متن کاملStone clustering of patients with cystine urinary stone formation.
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ژورنال
عنوان ژورنال: Notulae Scientia Biologicae
سال: 2023
ISSN: ['2067-3264', '2067-3205']
DOI: https://doi.org/10.55779/nsb15111462