Pathological bacterial translocation in liver cirrhosis
نویسندگان
چکیده
منابع مشابه
Bacterial translocation markers in liver cirrhosis
Bacterial translocation (BT) is an important mechanism in the development of infection in liver cirrhosis. The migration and colonization of bacteria and/or bacterial products from the bowel to mesenteric lymph nodes is a controlled process in healthy persons. Increased intestinal permeability, bacterial overgrowth and defect of gut-associated lymphatic tissue promote impaired BT in cirrhotics....
متن کاملBacterial translocation aggravates CCl4-induced liver cirrhosis by regulating CD4+ T cells in rats
Bacterial translocation (BT) is thought to play an important role in the development of liver cirrhosis, but the mechanisms have not been fully explored. This study aims to investigate the distribution of Treg (CD3+CD4+CD25+Foxp3+), Th17 (CD3+CD4+IL-17+), and Th1 (CD3+CD4+IFN-γ+) cells in the intestinal lamina propria, liver and blood and to explore their relationships with BT. Cirrhotic rats w...
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INTRODUCTION Liver cirrhosis is characterized by a reduced defensive reaction to bacterial infections and patients with cirrhosis are at increased risk of developing infections, sepsis and death. The most common bacterial infections in these patients are spontaneous bacterial peritonitis, urinary tract infection, pneumonia, skin and soft tissue infection and bacteremia. The most common causes a...
متن کاملPrevalence of spontaneous bacterial peritonitis in liver cirrhosis with ascites
OBJECTIVE The study was designed to elucidate the correlation of spontaneous bacterial peritonitis (SBP) with aetiology of liver cirrhosis, overall mortality, ascitic fluid and systemic microbial infections. METHODS Sixty three patients with cirrhosis of the liver were included in this study. These patients were diagnosed on the basis of clinical evaluation, biochemical investigation, ultraso...
متن کاملSpontaneous Bacterial Peritonitis and Bacteremia in Patients with Liver Cirrhosis
Patients with Liver Cirrhosis (LC) are at high risk of developing bacterial infections. Pathological bacterial translocation has been implicated as an important cause of bacterial infection in patients with LC, and Spontaneous Bacterial Peritonitis (SBP) and bacteremia are common and often fatal bacterial infections in these patients. Moreover, the incidence of hepatorenal syndrome is associate...
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ژورنال
عنوان ژورنال: Journal of Hepatology
سال: 2014
ISSN: 0168-8278
DOI: 10.1016/j.jhep.2013.07.044