Pathogenic Mechanisms of Acute Obstructive Pyelonephritis

Among urological diseases, the most relevant is infection of urinary tract. Pyelonephritis on 5th place in kidney and obstructive pyelonephritis occurs 84% all pyelonephritis. In world, among adult population, 100 people per 100,000 population suffer from addition, year to year, there an increase purulent forms acute by 4–5 times. This pathology a separated manifestation such important problem as complicated tract infection, which accounts for 84–86% infections. pyelonephritis, more severe complications bacteriotoxic shock urosepsis may develop. The mortality rate these dangerous reaches 70–90%. number patients with has increased 4–6 times recent years. review presents current literature data main causes pathogenetic mechanisms disease development are presented.