Pathogenic mechanisms in unstable angina

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Pathophysiologic Mechanisms in Unstable Angina

UNDERSTANDING the pathophysiology of unstable angina has been a major research effort for over two decades. Over the years our understanding of this syndrome has changed as different causes for the syndrome were identified. Initially, it was thought that increased myocardial oxygen demand was responsible for rest ischemia in patients with unstable angina. Later, it seemed that decreased supply ...

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NMR-based plasma metabolic profiling in patients with unstable angina

Objective(s): Unstable angina (UA) is a form of the acute coronary syndrome (ACS) that affects more than a third of the population before age 70. Due to the limitations of diagnostic tests, appropriate identification of UA is difficult. In this study, we proceeded to investigate metabolite profiling in UA patients compared with controls to determine potential candidate...

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Unstable angina.

Unstable angina has only been recognized as a distinct entity for about 50 years. The term is used to describe a symptom complex that is neither stable angina pectoris nor acute myocardial infarction. There are a number of other terms used to describe essentially the same symptom complex; these include pre-infarction angina, crescendo angina, intermediate coronary syndrome and threatening infar...

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Unstable Angina

Identification of a characteristic morphology of a coronary stenosis likely to result in myocardial infarction would facilitate the prospective evaluation of infarct prevention strategies and identification of high-risk patients. We postulated that coronary lesions associated with recent myocardial infarction or unstable angina would have an angiographic morphology suggesting disruption of an a...

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Prognosis in unstable angina.

A retrospective study was made of 158 patients with unstable angina admitted to a coronary care unit over a 4-year period. Twenty patients (13 per cent) had myocardial infarcts while in hospital, and of these 3 died; three others died without preceding evidence of myocardial infarction. There was thus an acute mortality rate of 4 per cent. Patients with persisting angina after the first 24 hour...

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ژورنال

عنوان ژورنال: Heart

سال: 1999

ISSN: 1355-6037

DOI: 10.1136/hrt.82.2008.i2