منابع مشابه
Epidemiology and pathogenesis of influenza.
Influenza A, B and C all have a segmented genome, although only certain influenza A subtypes and influenza B cause severe disease in humans. The two major proteins of influenza are the surface glycoproteins-haemagglutinin (HA) and neuraminidase (NA). HA is the major antigen for neutralizing antibodies and is involved in the binding of virus particles to receptors on host cells. Pandemics are a ...
متن کاملCytokines in the pathogenesis of influenza.
Uncomplicated influenza in humans, horses or swine is characterized by massive virus replication in respiratory epithelial cells, inflammation and an abrupt onset of general and respiratory disease. There is now growing evidence that the so-called early cytokines produced at the site of infection mediate many of the clinical and pathological manifestations. Among these cytokines are interferon-...
متن کاملPathogenesis of Influenza D Virus in Cattle.
UNLABELLED Cattle have been proposed as the natural reservoir of a novel member of the virus family Orthomyxoviridae, which has been tentatively classified as influenza D virus (IDV). Although isolated from sick animals, it is unclear whether IDV causes any clinical disease in cattle. To address this aspect of Koch's postulates, three dairy calves (treatment animals) held in individual pens wer...
متن کاملPathogenesis of the 1918 Pandemic Influenza Virus
1 Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, 2 ERATO Infection-Induced Host Responses Project, Japan Science and Technology Agency, Saitama, Japan, 3 Division of Zoonosis, Department of Microbiology and Infectious Diseases, Graduate School of Medicine, Kobe Un...
متن کاملOf ferrets and humans: influenza pathogenesis.
In the current issue of the Journal, van den Brand and colleagues [1] report on the pathogenicity of seasonal H1N1 influenza virus, highly pathogenic avian influenza (HPAI) H5N1 virus, and the new 2009 H1N1 influenza virus strains after intratracheal inoculation into ferrets. They determine that the pulmonary pathoge-nicity of the 2009 H1N1 pandemic strain is intermediate between that of HPAI H...
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ژورنال
عنوان ژورنال: Bacteriological Reviews
سال: 1961
ISSN: 0005-3678
DOI: 10.1128/br.25.3.294-300.1961