منابع مشابه
Interleukin-6 expression on the biliary epithelia during inflammation-associated biliary carcinogenesis in bilioenterostomized hamsters.
BACKGROUND Chronic inflammatory conditions of the biliary tree strongly predispose patients to biliary carcinoma. The aim of this study was to evaluate the role of interleukin-6 (IL-6) expression during biliary carcinogenesis in bilioenterostomized hamsters. MATERIALS AND METHODS Syrian hamsters were subjected to either a choledochoduodenostomy (CD, n=11) or a simple laparotomy (SL, n=10) and...
متن کاملEditorial: betaretrovirus in biliary epithelia of patients with autoimmune and cryptogenic liver disease – authors’ reply
*Center of Excellence for Gastrointestinal Inflammation and Immunity Research, University of Alberta, Edmonton, AB, Canada. Department of Virology, University of Veterinary Medicine, Vienna, Austria. Department of Biological Sciences, University of Alberta, Edmonton, AB, Canada. BGI-Shenzhen, Bei Shan Industrial Zone, Shenzhen, China. Li Ka Shing Institute of Virology, University of Alberta, Ed...
متن کاملBiliary atresia--bile acids and prostaglandin E2 in cell cultures of bile duct epithelia.
In a cell culture model of bile duct epithelial cells, the effect of prostaglandin E2, lithocholic acid and deoxycholic acid was studied. Bile acids and prostaglandin are administered postoperatively in biliary atresia empirically as choleretics. Prostaglandin E2 and the bile acids all had inhibitory effects on bile duct epithelial cells in culture. There is no clinical study proving the effica...
متن کاملCryptosporidium parvum induces apoptosis in biliary epithelia by a Fas/Fas ligand-dependent mechanism.
Although the clinical features of sclerosing cholangitis from opportunistic infections of the biliary tree in patients with acquired immunodeficiency syndrome (AIDS) are well known, the mechanisms by which associated pathogens, such as Cryptosporidium parvum, cause disease are obscure. Using an in vitro model of biliary cryptosporidiosis, we observed that C. parvum induces apoptosis in cultured...
متن کاملExtracellular nucleotides stimulate Cl- currents in biliary epithelia through receptor-mediated IP3 and Ca2+ release.
Extracellular ATP regulates bile formation by binding to P2 receptors on cholangiocytes and stimulating transepithelial Cl(-) secretion. However, the specific signaling pathways linking receptor binding to Cl(-) channel activation are not known. Consequently, the aim of these studies in human Mz-Cha-1 biliary cells and normal rat cholangiocyte monolayers was to assess the intracellular pathways...
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ژورنال
عنوان ژورنال: Kanzo
سال: 1997
ISSN: 0451-4203,1881-3593
DOI: 10.2957/kanzo.38.supl2_54