Paternal age increases the risk for autism in an Iranian population sample

Paternal age increases the risk for autism in an Iranian population sample

BACKGROUND Autism is a neurodevelopmental disorder which is known to have a strong genetic component and is most likely oligogenic. However, the necessary role of environmental factors has been well documented. Prior research suggests that parental characteristics, such as age and level of education, may be associated with a risk of autism. Parental age has been shown to be associated with many...

Advancing Paternal Age and Risk of Autism

Risk of autism and increasing maternal and paternal age in a large north American population.

Previous studies are inconsistent regarding whether there are independent effects of maternal and paternal age on the risk of autism. Different biologic mechanisms are suggested by maternal and paternal age effects. The study population included all California singletons born in 1989-2002 (n = 7,550,026). Children with autism (n = 23,311) were identified through the California Department of Dev...

Advancing paternal age and autism.

CONTEXT Maternal and paternal ages are associated with neurodevelopmental disorders. OBJECTIVE To examine the relationship between advancing paternal age at birth of offspring and their risk of autism spectrum disorder (ASD). DESIGN Historical population-based cohort study. SETTING Identification of ASD cases from the Israeli draft board medical registry. PARTICIPANTS We conducted a stu...

Advanced paternal age increases risk of bipolar disorder in offspring.

ED FROM Frans EM, Sandin S, Reichenberg A, et al. Advancing paternal age and bipolar disorder. Arch Gen Psychiatry 2008;65:1034–40. Correspondence to: Emma M Frans, MMedSc, Department of Medical Epidemiology and Biostatistics, Karolinksa Institute, PO Box 281, SE-171 77 Stockholm, Sweden; [email protected] Source of funding: None reported. c A table is published online only at http://ebmh.bmj.co...