منابع مشابه
Paternal age and congenital malformations.
BACKGROUND Spontaneous mutations in germ cells increase with male age, but an association between paternal age and congenital malformations is not well established. We conducted a population-based cohort study to estimate this association. METHODS A study population of couples and their firstborn children were identified in the Danish Fertility Database between 1980 and 1996 (n = 71937). Diag...
متن کامل[Paternal age as a risk factor for congenital malformations].
BACKGROUND The role of advanced maternal age as a risk factor for congenital malformations in offspring is known. However, the influence of paternal age is not clear. AIM To evaluate the association between advanced paternal age and the risk for congenital malformations. PATIENTS AND METHODS Analysis of maternal and paternal age of cases (malformed newborns) and controls from ECLAMC Databas...
متن کاملPaternal occupational lead exposure and congenital malformations.
STUDY OBJECTIVE The aim was to investigate whether occupational exposure to lead in fathers is associated with congenital malformation in their children. DESIGN The study was a retrospective case-control study, nested within the wives of men biologically monitored for inorganic lead. Information on pregnancy outcome was obtained from medical registers. SUBJECTS Cases were defined as wives w...
متن کاملMusculoskeletal congenital malformations: do paternal occupational exposures play a role?
BACKGROUND Paternal occupational exposures to potential health hazards are likely to affect congenital malformations through the spermatogenesis cycle. PURPOSE The aim of this case-control study was to assess the relationship between the risk of musculoskeletal congenital malformations in offspring and paternal workplace exposure to potential health hazards during the preconception period. ...
متن کامل[The association between maternal age and congenital malformations].
BACKGROUND There is an association between extreme maternal ages and the risk of congenital malformations. This is specially true for chromosomal abnormalities among women of advanced ages and disruptive malformation among teenage mothers. AIM To determine the association between maternal ages and incidence of congenital malformations at the obstetric ward of a clinical hospital. To compare t...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 2005
ISSN: 1460-2350,0268-1161
DOI: 10.1093/humrep/dei186