Passive Protection of Lambs Against Experimental Enteric Colibacillosis by Colostral Transfer of Antibodies From K99-Vaccinated Ewes
نویسندگان
چکیده
منابع مشابه
Passive protective effect of anti-K99 antibodies against enterotoxigenic E.coli infection in neonatal calves
BACKGROUND: BACKGROUND: Enterotoxigenic Escherichia coli (ETEC) is the main causative agents of neonatal calf diarrhea. Passive transfer of antibodies that is derived from the dams of the calves through their colostrum plays an important role in disease prevention. OBJECTIVES: To determine the presence of natural specific antibodies against K99 antigen in dam’s serum and colostrum as well as in...
متن کاملVaccination of cows with a K99 extract to protect newborn calves against experimental enterotoxic colibacillosis.
Pregnant cows and heifers were vaccinated with a crude K99 extract prepared from an Escherichia coli K-12, K99 strain. A similar group, injected with an extract prepared from the K-12 parent strain, served as a control. Eleven calves were born to both groups and challenged orally with a mean of 1.6 x 10(11) bacteria of enterotoxic E. coli B41 (O101:K99+, ST+) at the time of first colostrum upta...
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Widespread vaccination programmes against Bluetongue virus serotype 8 (BTV-8), using inactivated vaccines, are being carried out across many countries in northern, western and southern Europe. This study investigates the extent and length of colostral antibody protection, as well as the degree of colostral antibody induced interference of the immune response to BTV-8, in sheep. Significantly lo...
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The ability of eight neutralizing monoclonal antibodies (MAbs) specific for structural proteins of murine cytomegalovirus (MCMV) to protect mice passively against MCMV infection was examined to determine firstly whether a correlation existed between the neutralization titres of the MAbs in vitro and the protection afforded by the MAbs in vivo and, secondly, the contribution of the host towards ...
متن کاملGlycoprotein glycans that inhibit adhesion of Escherichia coli mediated by K99 fimbriae: treatment of experimental colibacillosis.
Calf diarrhea due to infection by enterotoxigenic Escherichia coli was treated by administration of glycoprotein glycans derived from bovine plasma. The glycan moieties of the nonimmunoglobulin fraction of plasma mimicked the oligosaccharide moiety of intestinal receptors recognized by K99 pili. These glycoprotein glycans inhibited adhesion of E. coli K99+ ST+ to erythrocyte glycoconjugates in ...
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ژورنال
عنوان ژورنال: Journal of Medical Microbiology
سال: 1978
ISSN: 0022-2615,1473-5644
DOI: 10.1099/00222615-11-4-493