Particulate Alum via Pickering Emulsion for an Enhanced COVID‐19 Vaccine Adjuvant
نویسندگان
چکیده
منابع مشابه
GLA-AF, an Emulsion-Free Vaccine Adjuvant for Pandemic Influenza
The ongoing threat from Influenza necessitates the development of new vaccine and adjuvant technologies that can maximize vaccine immunogenicity, shorten production cycles, and increase global vaccine supply. Currently, the most successful adjuvants for Influenza vaccines are squalene-based oil-in-water emulsions. These adjuvants enhance seroprotective antibody titers to homologous and heterolo...
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The biodegradable cellular capsule, being prepared from simple vaporization of liquid marbles, is an ideal vehicle for the potential application of drug encapsulation and release. This paper reports the fabrication of cellular capsules via facile vaporization of Pickering emulsion marbles in an ambient atmosphere. Stable Pickering emulsion (water in oil) was prepared while utilizing dichloromet...
متن کاملEffect of alum co-adjuvantation of oil adjuvant vaccine on emulsion stability and immune responses against haemorhagic septicaemia in mice
BACKGROUND AND OBJECTIVES Haemorrhagic septicaemia (HS), caused by Pasteurella multocida, is the most important bacterial disease of cattle and buffaloes in India. Oil adjuvant vaccine (OAV) is the most potent vaccine available for the control of HS. The study aims to evaluate the effect of alum co-adjuvantation of OAV on emulsion stability and immune response. MATERIALS AND METHODS Two diffe...
متن کاملMaterial : Aging mechanism in model Pickering emulsion
The chemicals used for the NPs synthesis are TetraEthylOrthoSilicate (TEOS), l-Arginine, chloride acid 0.1M and ethanol. They were supplied by Aldrich and used as received. High-purity deionized water (18.2 M.cm) was produced using Millipore Milli-Q Gradient system. The synthesis follows the same protocol as in our previous work [1]. It is performed in a 2000 ml reactor thermostated with hot wa...
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ژورنال
عنوان ژورنال: Advanced Materials
سال: 2020
ISSN: 0935-9648,1521-4095
DOI: 10.1002/adma.202004210