Particulate Air Pollution Exposure and C-reactive Protein During Early Pregnancy

Particulate air pollution exposure and C-reactive protein during early pregnancy.

BACKGROUND It is not well understood how air pollution leads to adverse pregnancy outcomes. One pathway may be through C-reactive protein, a biomarker of systemic inflammation that has been reported to increase the risk of preterm delivery. We examined whether air pollution influences serum concentrations of C-reactive protein in early pregnancy. METHODS We studied 1696 pregnant women in Alle...

Chronic Air Pollution Exposure during Pregnancy and Maternal and Fetal C-Reactive Protein Levels: The Generation R Study

BACKGROUND Exposure to air pollution has been associated with higher C-reactive protein (CRP) levels, suggesting an inflammatory response. Not much is known about this association in pregnancy. OBJECTIVES We investigated the associations of air pollution exposure during pregnancy with maternal and fetal CRP levels in a population-based cohort study in the Netherlands. METHODS Particulate ma...

Air Pollution Exposure During Pregnancy and Reproductive Outcomes

Disparities in exposure to air pollution during pregnancy.

Previous research shows poorer birth outcomes for racial and ethnic minorities and for persons with low socioeconomic status (SES). We evaluated whether mothers in groups at higher risk for poor birth outcomes live in areas of higher air pollution and whether higher exposure to air pollution contributes to poor birth outcomes. An index representing long-term exposure to criteria air pollutants ...

Air pollution exposure in early pregnancy and adverse pregnancy outcomes: a register-based cohort study

OBJECTIVES Our aim was to study the possible associations between exposure to elevated levels of air pollution, ozone (O(3)) and vehicle exhaust (NO(x)), during early gestation, and adverse pregnancy outcomes such as pre-eclampsia, preterm birth and small for gestational age. DESIGN Prospective register-based cohort study. SETTING The Swedish Medical Birth Register includes data on all deli...