منابع مشابه
Localized gigantism
A 28-year-old male patient presented to us with the history of swelling over the left foot, the proximal left leg, and another separate swelling over the left greater trochanteric region since birth. The rate of enlargement of digits was disproportionate to age. For the last 2 years, he started complaining of decreased sensation over the dorsum of the left foot and sole. The physical examinatio...
متن کاملFamilial gigantism
Familial GH-secreting tumors are seen in association with three separate hereditary clinical syndromes: multiple endocrine neoplasia type 1, Carney complex, and familial isolated pituitary adenomas.
متن کاملPituitary gigantism.
A case of pituitary gigantism resulting from a pituitary adenoma which secreted growth hormone is described. The patient was successfully treated by surgery, which led to the normalisation of endogenous growth hormone secretion. An acceptable final height was achieved with high dose intramuscular testosterone treatment.
متن کاملAcromegaly and Gigantism
Human growth hormone (GH), a single-chain peptide of 191 amino acids, was isolated from somatotroph cells of the anterior pituitary gland in 1956 and first used therapeutically for treatment of pituitary dwarfism in 1958 (Raben, 1958). Pituitary dwarfism is the classic form of growth hormone deficiency during childhood. Gigantism refers to any standing height more than 2 standard deviations abo...
متن کاملFloral gigantism in Rafflesiaceae.
Species of Rafflesiaceae possess the world's largest flowers (up to 1 meter in diameter), yet their precise evolutionary relationships have been elusive, hindering our understanding of the evolution of their extraordinary reproductive morphology. We present results of phylogenetic analyses of mitochondrial, nuclear, and plastid data showing that Rafflesiaceae are derived from within Euphorbiace...
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ژورنال
عنوان ژورنال: INTERNATIONAL JOURNAL OF ENDOCRINOLOGY
سال: 2017
ISSN: 2307-1427,2224-0721
DOI: 10.22141/2224-0721.13.4.2017.106661