Paroxysmal Discharges of Cat's Cerebral Cortex treated with Gamma Aminobutyric Acid
نویسندگان
چکیده
منابع مشابه
Effect of diisopropylfluorophosphate on muscarinic and gamma-aminobutyric acid receptors in visual cortex of cats.
Administration of diisopropylfluorophosphate (DFP), an organophosphorus (OP) compound, irreversibly inhibits acetylcholinesterase (AChE) and results in cholinergic hyperactivity. This study investigated muscarinic and gamma-aminobutyric acid (GABA) receptor changes in visual cortex of cats following an acute exposure to DFP. A single acute administration of DFP (4 mg/kg) decreased the number of...
متن کاملVertical organization of gamma-aminobutyric acid-accumulating intrinsic neuronal systems in monkey cerebral cortex.
Light and electron microscopic methods were used to examine the neurons in the monkey cerebral cortex labeled autoradiographically following the uptake and transport of [3H]-gamma-aminobutyric acid (GABA). Nonpyramidal cell somata in the sensory-motor areas and primary visual area (area 17) were labeled close to the injection site and at distances of 1 to 1.5 mm beyond the injection site, indic...
متن کاملA y-Aminobutyric Acid/Benzodiazepine Receptor Cerebral Cortex
The y-aminobutyric acid/benzodiazepine receptor from bovine cerebral cortex was solubilized with sodium deoxycholate and purified by affinity chromatography on benzodiazepine-agarose and ion exchange chromatography. The benzodiazepine binding protein was enriched 1800-fold. Polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate and dithiothreitol showed the presence of two...
متن کاملGamma-Aminobutyric Acid (GABA) Monograpy
Introduction Gamma-aminobutyric acid (GABA) is a major neuro transmitter widely distributed throughout the central nervous system (CNS). Because too much excitation can lead to irritability, restlessness, insomnia, seizures, and movement disorders, it must be balanced with inhibition. GABA – the most important inhibitory neurotransmitter in the brain – provides this inhibition, acting like a “b...
متن کاملSensorimotor cortex gamma-aminobutyric acid concentration correlates with impaired performance in patients with MS.
BACKGROUND AND PURPOSE Abnormalities in GABA concentration [GABA] have been associated with several neuropsychiatric disorders, and research has suggested that GABA may play a role in sensorimotor cortex function. We sought to determine whether identifying a change in [GABA] within the sensorimotor cortex of patients with MS has any effect on motor function and would provide information about t...
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ژورنال
عنوان ژورنال: The Tohoku Journal of Experimental Medicine
سال: 1960
ISSN: 0040-8727,1349-3329
DOI: 10.1620/tjem.72.366