Parathyroid Hormone for Treatment of Osteoporosis

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Safety of parathyroid hormone for the treatment of osteoporosis.

Teriparatide (recombinant human 1-34 parathyroid hormone) has been registered for the treatment of postmenopausal osteoporosis and osteoporosis in men for more than 5 years, whereas 1-84 parathyroid hormone has just recently been registered in Europe for osteoporosis management. Therefore, more data are available regarding the long-term safety of teriparatide. The issues to be considered are th...

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Parathyroid hormone for the treatment of osteoporosis: a systematic review.

BACKGROUND Human parathyroid hormone (hPTH)(1-34) was approved in 2004 for the treatment of severe osteoporosis. Members of the Osteoporosis Canada clinical guidelines committee conducted a systematic review of randomized controlled trials (RCTs) to assess the efficacy and safety of hPTH for fracture prevention in postmenopausal women and men with osteoporosis. METHODS We searched MEDLINE, EM...

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Treatment of osteoporosis in a mouse model of Duchenne muscular dystrophy using black bear parathyroid hormone

...................................................................................................................................... 13 1 4BIntroduction...................................................................................................................... 14 1.1 11BOsteoporosis Background................................................................................. 14 1.2 12...

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Full length parathyroid hormone (1–84) in the treatment of osteoporosis in postmenopausal women

OBJECTIVE To review the pharmacological properties and the available clinical data of full length parathyroid hormone (PTH) in post-menopausal osteoporosis. SOURCES A MEDLINE search was completed, together with a review of information obtained from the manufacturer and from the medicine regulatory agencies. STUDY AND DATA SELECTION: Studies were selected according to relevance and availabilit...

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Parathyroid hormone treatment can reverse corticosteroid-induced osteoporosis. Results of a randomized controlled clinical trial.

Corticosteroid-induced osteoporosis is the most common secondary cause of osteoporosis. We conducted a 12-mo, randomized clinical trial of human parathyroid hormone 1-34 (hPTH 1-34) in postmenopausal women (mean age was 63 yr) with osteoporosis who were taking corticosteroids and hormone replacement therapy. Response to the treatment was assessed with bone mineral density (BMD) measurements of ...

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ژورنال

عنوان ژورنال: Archives of Internal Medicine

سال: 2002

ISSN: 0003-9926

DOI: 10.1001/archinte.162.20.2297