Parasympathetic Nervous System and Heart Failure
نویسندگان
چکیده
منابع مشابه
Parasympathetic nervous system and heart failure: pathophysiology and potential implications for therapy.
Abundant evidence links sympathetic nervous system activation to outcomes of patients with heart failure (HF).1 In contrast, parasympathetic activation has complex cardiovascular effects that are only beginning to be recognized. In particular, the pathophysiological roles of normal and disordered parasympathetic innervation in patients with HF are not understood as comprehensively.2–5 In the pr...
متن کاملThe sympathetic nervous system and heart failure.
Heart failure (HF) is a syndrome characterized by upregulation of the sympathetic nervous system and abnormal responsiveness of the parasympathetic nervous system. Studies in the 1980s and 1990s demonstrated that inhibition of the renin-angiotensin-aldosterone system with angiotensin-converting enzyme inhibitors improved symptoms and mortality in HF resulting from systolic dysfunction, thus pro...
متن کاملThe autonomic nervous system and heart failure.
The pathophysiology of heart failure (HF) is characterized by hemodynamic abnormalities that result in neurohormonal activation and autonomic imbalance with increase in sympathetic activity and withdrawal of vagal activity. Alterations in receptor activation from this autonomic imbalance may have profound effects on cardiac function and structure. Inhibition of the sympathetic drive to the hear...
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Not the least of the many attributes essential to the really good book is readability,-especially readability by that group most likely to benefit by the reading. To attain such a quality, when the subject matter deals with scientific fact, is, indeed, difficult unless the exposition is designed to serve those who are specialists in the field covered. Thus it is that most texts become so encumb...
متن کاملSympathetic nervous system in heart failure.
For those who have comfortably accepted the mechanistic link between sympathetic nervous system activation and poor outcome in heart failure, the study by Brede et al1 in this issue of Circulation is a welcome confirmation. The authors appear to have demonstrated in a murine model that absence of sympathoinhibitory 2 adrenoreceptors is associated with overactive catecholamine release, aggressiv...
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ژورنال
عنوان ژورنال: Circulation
سال: 2008
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.107.760405