Paraneoplastic Leukocytosis: A Poor Prognostic Marker in Pancreatic Adenocarcinoma

Low expression of aldehyde deyhdrogenase 1 (ALDH1) is a prognostic marker for poor survival in pancreatic cancer Running title: ALDH-1 is a prognostic marker in pancreatic cancer

Podocalyxin Is a Marker of Poor Prognosis in Pancreatic Ductal Adenocarcinoma

AIM OF THE STUDY Podocalyxin-like 1 is a transmembrane glyco-protein whose overexpression associates in many cancers with poor prognosis and unfavorable clinicopathological characteristics. Until now, its prognostic value has never been studied in pancreatic ductal adenocarcinoma (PDAC). The aim of this study was to investigate podocalyxin expression in PDAC by a novel monoclonal antibody and a...

PDGFRβ expression in tumor stroma of pancreatic adenocarcinoma as a reliable prognostic marker.

Pancreatic adenocarcinoma is a lethal disease that often develops a desmoplastic reaction in tumor stroma. In general, desmoplasia is thought to promote tumor growth. However, its molecular pathology and prognostic potential have not been fully investigated. Here, we investigate 26 cases of pancreatic ductal adenocarcinoma and examine the clinicopathological association between survival and exp...

Clinical Significance of Circulating Tumor Microemboli as a Prognostic Marker in Patients with Pancreatic Ductal Adenocarcinoma.

BACKGROUND Characterization of circulating tumor cells (CTCs) has been used to provide prognostic, predictive, and pharmacodynamic information in many different cancers. However, the clinical significance of CTCs and circulating tumor microemboli (CTM) in patients with pancreatic ductal adenocarcinoma (PDAC) has yet to be determined. METHODS In this prospective study, CTCs and CTM were enumer...

Exocrine pancreatic adenocarcinoma in a toy breed dog

A 4-year-old female miniature pincher with a 40-day history of weight loss, lethargy and vomiting was referred to Small Animal Hospital, Faculty of Veterinary Medicine, University of Tehran. The case also had severe jaundice, chronic diarrhoea and steatorrhoea. The efforts for saving the life of the case were not successful and finally the animal died of hypovolaemic shock and electrolyte imbal...