Paradoxical bronchoconstriction and salmeterol.
نویسندگان
چکیده
منابع مشابه
Paradoxical bronchoconstriction in asthmatic patients after salmeterol by metered dose inhaler.
BMJ 1992;305:931-2 be assumed not to be., planning a pregnancy. A treatment which minimised the likelihood of a delayed bleed, and therefore the requirement for a pregnancy test, would seem advantageous. The three pregnancies conceived after mifepristone treatment suggests that the next cycle and ovulation may occur without an intervening bleed. As we found no true failures of mifepristone trea...
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enhancement of excitatory signals such as Glutamate [12]. Serotonin plays a dual (may be synergistic effect) role in increasing susceptibility to seizures. Firstly through 5-HT 2A receptors (as mentioned above) and secondly through its effects on sleep; on the one hand, it promotes NREM sleep (NREM increases susceptibility to seizures), while on the other hand it exerts inhibitory role in actua...
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Salmeterol provides bronchoprotection against a number of constrictor stimuli for more than 12 h after a single dose. This effect could be due either to functional antagonism at the level of airway smooth muscle or to cell-stabilizing effects of the compound. In this study, we attempted to clarify this mechanism by comparing the effects of salmeterol (50 micrograms), salbutamol (200 micrograms)...
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The onset of the bronchodilating effect of formoterol (12 microg by Turbuhaler) was compared with that of salbutamol (50 microg by Turbuhaler), salmeterol (50 microg by Diskhaler) and placebo in methacholine-induced severe bronchoconstriction. Seventeen subjects with mild-to-moderate asthma completed this randomized, double blind, cross-over, double-dummy study. On four study days, baseline for...
متن کاملFailure of salmeterol to inhibit circulating white cell responses and bronchoconstriction induced by platelet activating factor.
BACKGROUND Platelet activating factor (PAF) is a potent mediator of inflammation. Inhalation of PAF causes acute bronchoconstriction and a transient fall in white blood cell count in humans. Salmeterol inhibits pulmonary inflammation induced by PAF in guinea pigs. METHODS The effect of salmeterol on effects induced by PAF was investigated in eight normal subjects who inhaled salmeterol (50 mi...
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ژورنال
عنوان ژورنال: BMJ
سال: 1992
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.305.6862.1161