Paracetamol in suicide and non-accidental overdose--are restrictions justified?

Use of paracetamol for suicide and non-fatal poisoning in the UK and France: are restrictions on availability justified?

OBJECTIVE To investigate the relationship between the availability of paracetamol and its use for overdose and suicide. DESIGN Analysis of routinely collected information on time trends for paracetamol suicides, non-fatal overdoses, and sales. SETTING England and Wales and France. RESULTS There were strong correlations between trends in paracetamol sales in the UK and trends in non-fatal ...

Accidental intrathecal methotrexate overdose.

Paracetamol availability and overdose in Ireland.

New regulations for the control of paracetamol come into force in October 2001. These are greatly welcomed and should lead to a reduction in paracetamol poisoning. Existing conditions for the sale and supply of paracetamol (Irish Medicines Board (IMB), 1997), which have no statutory basis, state that non-pharmacy outlets should only sell emergency supplies of paracetamol in a maximum pack size ...

Liver transplantation after paracetamol overdose.

OBJECTIVE To evaluate the role of liver transplantation after paracetamol overdose. DESIGN Prospective study of consecutive candidates for transplantation and performance of transplantation over 18 months. SETTING Liver unit, King's College Hospital, London. MAIN OUTCOME MEASURES Fulfilment of indicators of poor prognosis, selection for transplantation, transplantation, survival. RESULT...

Severe thrombocytopenia after paracetamol overdose.

Two patients with severe thrombocytopenia after paracetamol overdose are described. The platelet count was lowest two days after the overdose. Neither leucopenia nor anaemia occurred.