Pankreatikoduodenektomili hastalarda albümin/globulin oranının postoperatif pankreas fistülünü öngörmedeki rolü

Background: The albumin/globulin ratio (AGR) is one of several indicators inflammation and immunity. This has a prognostic significance in many malignant diseases. Previous studies have demonstrated relationship between inflammatory mediators post-operative pancreatic fistula (POPF). study aimed to evaluate the AGR, relatively new indicator, with (POPF).
 Methods: Pancreaticoduodenectomy (PD) patients 2017 2020 were retrospectively analyzed divided into two groups: (1) (2) without clinically relevant POPF (CR-POPF). groups compared terms pre-operative–post-operative AGR clinicodemographic characteristics. was calculated as albumin/total protein–albumin, cutoff point for determined according Youden’s index.
 Results: CR-POPF developed 21% 121 who underwent PD. No differences age, gender, comorbid disease status, duct width, anastomosis technique found. Pre- day-3 (POD3) albumin levels found be significantly lower group. Multivariate analysis showed that tissue stiffness are independent risk factors development.
 Conclusion: Low an factor development CR-POPF. To reduce incidence POPF, this should maintained at optimal level. use useful tool predicting pancreaticoduodenectomy suggested.