Pancreatic Stromal Gremlin 1 Expression during Pancreatic Tumorigenesis
نویسندگان
چکیده
منابع مشابه
B Cells Promote Pancreatic Tumorigenesis.
Three recent studies, approaching the question from different angles and using different and/or overlapping models, provide compelling evidence for the involvement of tumor-infiltrating B cells in the initiation and progression of pancreatic ductal adenocarcinoma. These studies highlight the need for a better understanding of pancreatic tumor-immune system interactions and the immunologic mecha...
متن کاملMUC13 mucin augments pancreatic tumorigenesis.
The high death rate of pancreatic cancer is attributed to the lack of reliable methods for early detection and underlying molecular mechanisms of its aggressive pathogenesis. Although MUC13, a newly identified transmembrane mucin, is known to be aberrantly expressed in ovarian and gastro-intestinal cancers, its role in pancreatic cancer is unknown. Herein, we investigated the expression profile...
متن کاملNotch gene expression during pancreatic organogenesis
Notch receptors are involved in regulating the balance between cell differentiation and stem cell proliferation during the development of numerous tissues (Artavanis-Tsakonas, S., Matsuno, K., Fortini, M. E., 1995. Notch signaling. Science 268, 225-232). Here the expression of all four vertebrate Notch genes, their ligands, and some down-stream targets is analyzed during mouse pancreatic organo...
متن کاملpancreatic metastasis from rectal gastrointestinal stromal tumor: a case report
gastrointestinal stromal tumors are mesenchymal neoplasms of the gastrointesti- nal tract that originate from all areas of the gastrointestinal tract. metastases to the liver, peritoneum, bones, lungs and soft tissues have been reported. we present the case of a 47- year-old woman with rectal gastrointestinal stromal tumor that underwent wide local excision. she was treated with imatinib for a ...
متن کاملTherapeutic Discovery MUC13 Mucin Augments Pancreatic Tumorigenesis
The high death rate of pancreatic cancer is attributed to the lack of reliable methods for early detection and underlying molecular mechanisms of its aggressive pathogenesis. Although MUC13, a newly identified transmembranemucin, is known to be aberrantly expressed in ovarian and gastro-intestinal cancers, its role in pancreatic cancer is unknown. Herein, we investigated the expression profile ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genes & Diseases
سال: 2020
ISSN: 2352-3042
DOI: 10.1016/j.gendis.2020.05.001