Pancreatic Digestion

The digestion in vitro of triglycerides by pancreatic lipase.

The formation of partial glycerides by the hydrolysis in vitro of triglycerides with pancreatic lipase was first reported by Artom and Reale (1) and then again several years later by Frazer and Sammons (2). In these studies apparently no attention was paid to the isomeric form of the digestion products. Desnuelle et al. (3) further studied the hydrolysis of triglycerides and showed it to be a s...

Starch Origin and Thermal Processing Affect Starch Digestion in a Minipig Model of Pancreatic Exocrine Insufficiency

Although steatorrhea is the most obvious symptom of pancreatic exocrine insufficiency (PEI), enzymatic digestion of protein and starch is also impaired. Low praecaecal digestibility of starch causes a forced microbial fermentation accounting for energy losses and meteorism. To optimise dietetic measures, knowledge of praecaecal digestibility of starch is needed but such information from PEI pat...

Digestion of proteoglycans in porcine pancreatic elastase-induced emphysema in rats

Changes in the intraluminal protein digestion of pancreatic duct-ligated rats.

After ligature of the pancreatic duct (PDL), the body weight of rats decreased for several days, but began to increase from day 7, returning to that at the time of the operation on day 14. In these PDL animals, the weight gain was not due to improved digestion resulting from duodenal leakage of pancreatic enzymes or a compensatory increase of proteolytic enzyme activities in the intestinal muco...

Isolation of Rodent Pancreatic Acinar Cells and Acini by Collagenase Digestion

Isolated pancreatic acini and acinar cells can be prepared from rat, mouse, and guinea pig pancreas using a collagenase digestion and used for studies of secretion, ligand binding, substrate uptake, protein synthesis and second messenger generation. Acinar size and integrity are highly dependent on the type of collagenase used and the application of shearing forces. After digestion acini can be...