Panax Ginseng Inhibits Maximal Electroshock Induced Convulsions in Mice
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منابع مشابه
Paeoniflorin Diminishes Maximal Electroshock - and PTZ - induced Convulsions in Mice
Paeonia Radix is one of the most commonly used herbal drug in traditional Chinese medicine1 and folkloric medicine of different countries since ancient times2. A number of chemical and pharmacological studies have been conducted on the roots of Paeonia species. Monoterpen glycosides are the active constituents, among them; paeoniflorin is the main compound in genus Paeonia3. In traditional medi...
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Nefopam is a centrally acting non-opioid analgesic with a mechanism of action that is not completely understood. Adverse effects associated with the therapeutic use and overdose of nefopam are mainly associated with the central nervous system, such as hallucinations, cerebral edema and convulsions. The aim of this study was to assess the effect of nefopam on the electrical threshold and its inf...
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Orphenadrine is an anticholinergic drug used in the treatment of Parkinson's disease, and is also known to exert nonspecific antagonistic activity at the phencyclidine binding site of the N-methyl-D-aspartate (NMDA) receptor. The aim of this study was to assess the anticonvulsant properties of orphenadrine and to evaluate its effect on the anticonvulsant activity of antiepileptic drugs against ...
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Allopurinol, an inhibitor of xanthine oxidase, is indicated in the management of patients with elevated serum and urinary uric acid levels. It was also reported to be beneficial in patients with epilepsy when added to traditional antiepileptic drug. Here, we investigated the effect of allopurinol upon the electrical seizure threshold and its effect on the protective efficacy of common antiepile...
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Background: Recently, there has been much more interest in the use of medicinal plants in search of novel therapies for human neurodegenerative diseases such as epilepsy. In the present study, we investigated the anticonvulsant effects of Viola tricolor (V. tricolor) on seizure models induced by pentylenetetrazol (PTZ) and maximal electroshock stimulation (MES). Methods: Totally, 260 mice were ...
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ژورنال
عنوان ژورنال: Egyptian Journal of Basic and Clinical Pharmacology
سال: 2020
ISSN: 2090-7230,2090-7222
DOI: 10.32527/2020/101381