Panax ginseng ameliorate toxic effects of cadmium on germ cell apoptosis, sperm quality, and oxidative stress in male Wistar rats

Panax ginseng is known to potentiate the immune system via its antioxidant properties. Cadmium as an environmental pollutant has destructive effects on body organs especially reproductive system. This study investigated of P. extract against cadmium-induced testicular toxicity in rats. In this experimental study, 50 male adult rats were randomly divided into 5 groups: A significant decrease was observed sperm count and viability cadmium group versus control group. Ginseng could repair these defects. Increases apoptotic germ cells due significantly reduced by extract. Our results demonstrated that reduces toxicity, anti-oxidative anti-apoptotic processes.