Pan Genotypic Response to Combination Treatment With Sofosbuvir and Daclatasvir in Chronic Hepatitis C Patients
نویسندگان
چکیده
منابع مشابه
Sofosbuvir and daclatasvir combination therapy in a liver transplant recipient with severe recurrent cholestatic hepatitis C.
Recurrent HCV infection following liver transplantation can lead to accelerated allograft injury that is difficult to treat with interferon. The aim of this study is to describe the first ever use of an interferon-free, all oral regimen in a liver transplant recipient with severe recurrent HCV. A 54-year-old male with HCV genotype 1b developed severe cholestatic HCV at 6 months posttransplant w...
متن کاملefficacy of locally manufactured sofosbuvir and daclatasvir (sovodak) in combination with ribavirin in treating patients with chronic hepatitis c and cirrhosis in iran – preliminary report
background: interferon-free treatments for hepatitis c have been recently available. they can cure over 95% of patients within 12 weeks without significant side effects. a combination of daclatasvir and sofosbuvir has been particularly useful as it is effective against all genotypes of hepatitis c virus (hcv). the combination of sofosbuvir and daclatasvir in a single pill has been recently manu...
متن کاملRapid virological&End treatment response of patients treated with Sofosbuvir in Chronic Hepatitis C
OBJECTIVE To determineRapid & End treatment response of patients treated with Sofosbuvir in Chronic Hepatitis C at tertiary care hospital. METHODS It was an observational study conducted at Memon Medical Institute from January 2016 to July 2017. The inclusion criteria for patients was 18 years of age or older, having chronic infection with HCV. Total=201 received sofosbuvir with or without in...
متن کاملReal-life efficacy of generic sofosbuvir/ledipasvir for treatment of Iranian patients with chronic hepatitis C: A cohort study
Background: Treatment of hepatitis C virus (HCV) infection with recently introduced direct-acting antiviral agents (DAA) is effective and safe, however there is little known regarding safety and efficacy of generic DAAs in the real-life clinical setting. This study aimed to evaluate the efficacy and safety of generic sofosbuvir/ledipasvir (SOF/LDV) in a real-life clinical experience. Methods: ...
متن کاملSofosbuvir and daclatasvir in mono- and HIV-coinfected patients with recurrent hepatitis C after liver transplant.
Background and aims. Pegylated interferon (Peg-INF) and ribavirin (RBV) based therapy is suboptimal and poorly tolerated. We evaluated the safety, tolerability and efficacy of a 24-week course of sofosbuvir plus daclatasvir without ribavirin for the treatment of hepatitis C virus (HCV) recurrence after liver transplantation (LT) in both HCV-monoinfected and human immunodeficiency virus (HIV)-H...
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ژورنال
عنوان ژورنال: Journal of Clinical and Experimental Hepatology
سال: 2017
ISSN: 0973-6883
DOI: 10.1016/j.jceh.2017.05.058