Pamidronate treatment in patient developed hypercalcemia due to hypervitaminosis D

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Hypercalcemia due to hypervitaminosis D: report of seven patients.

We retrospectively studied seven children (six girls, one boy) aged from 7.5 to 25 months who presented to our institution after taking large doses of vitamin D (900 000-4 000 000 U) prescribed by medical practitioners for wrong indications like failure to thrive, etc. The clinical manifestations were constipation, decreased appetite, lethargy, polyuria, dehydration and failure to thrive. All p...

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vitamin d intoxication with hypercalcemia due to overuse of supplement

we describe a patient with hypercalcemia associated with the injection of high doses vitamin d as supplement for a period of six months. a 76-year-old woman had been taking an intramuscular injection of vitamin d 300,000 iu every ten days for six months. she was hospitalized with symptoms of hypercalcemia: chronic constipation, unstable gait, a chronic generalized musculoskeletal pain and incre...

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Pamidronate therapy for hypercalcemia of childhood malignancy

Background Hypercalcemia is a common complication of adult malignancies, but uncommon in childhood cancers. The mechanism leading to hypercalcemia varies with the primary tumour and can include the following: 1) Increased osteoclastic activity at the site of the tumour in the bone marrow 2) A paraneoplastic phenomenon secondary to PTH-related peptide (PTHrP) secretion or 1,25–dihydroxyvitamin D...

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Pamidronate treatment in patients with tumor-associated hypercalcemia: pharmacological effects and pharmacokinetics.

The purpose of this study was to investigate the effects of pamidronate, a second generation bisphosphonate, on the change in calcium homeostasis in patients with tumor-associated hypercalcemia. Eight patients with tumor-associated hypercalcemia received intravenous infusion of pamidronate (45 mg) and their high mean serum calcium concentration significantly decreased from 3.56 mmol/L to 2.62 m...

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A Patient Developed Painful Muscle Cramps due to Overeating Mangos

A 79-year-old woman had a habit to eat a mango every night before sleep and experienced muscle cramps during sleep. Her muscle cramps may be resulted from potassium overload due to overeating mangos.

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ژورنال

عنوان ژورنال: SiSli Etfal Hastanesi Tip Bulteni / The Medical Bulletin of Sisli Hospital

سال: 2014

ISSN: 1302-7123,1308-5123

DOI: 10.5350/semb.20140715062539