PALM AND SOLE STUDIES PT. I-IV

Abruption pustular gouty tophi of palm and sole.

The authors present a case of a 70-year-old female who abruptly developed deep-seated pustule at both palms and soles. Aspiration content of the papule for gram's stain revealed needle-shaped materials with negative birefringence polarized light examination. Histological examination revealed deposition of amorphous materials surrounded by histiocytes, multinucleated giant cells, and lymphocytes...

Synthesis and characterization of Pt(IV) fluorescein conjugates to investigate Pt(IV) intracellular transformations.

Pt(IV) anticancer compounds typically operate as prodrugs that are reduced in the hypoxic environment of cancer cells, losing two axial ligands in the process to generate active Pt(II) species. Here we report the synthesis of two fluorescent Pt(IV) prodrugs of cisplatin in order to image and evaluate the Pt(IV) reduction process in simulated and real biological environments. Treatment of the co...

Cyclometalated Pt(IV) trans-diiodo adducts: experimental and computational studies within an homologous series of compounds.

Four cyclometalated Pt(IV) compounds, 1a,b and 2a,b, were successfully obtained by oxidative addition of I(2) to 2-phenylpyridinate (PhPy) and Nile Red (NR) derived Pt(II) complexes with acetylacetonate (acac) or hexafluoroacetylacetonate (hacac) ancillary ligands. Single crystal X-ray diffraction, electrochemical, photophysical and computational studies have been performed in comparison with t...

postnatal studies of bats (pipistrellus kuhlii and miniopterus schreibersii) & histomorphology and histochemistry studies of organs and diseases of (neurergus microspilotus and n. kaiseri)

1. to determine whether difference in birth body mass influenced growth performance in pipistrellus kuhlii we studied a total of 12 captive-born neonates. bats were assigned to two body mass groups: light birth body mass (lbw: 0.89 ± 0.05, n=8) and heavy birth body mass (hbw: 1.35 ± 0.08, n=4). heavier body mass at birth was associated with rapid postnatal growth (body mass and forearm length) ...

Catechism Series. Anatomy, Pt. I