Paclitaxel loading in PLGA nanospheres affected the in vitro drug cell accumulation and antiproliferative activity
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چکیده
منابع مشابه
Docetaxel loaded PEG-PLGA nanoparticles: optimized drug loading, in vitro cytotoxicity and in vivo antitumor effect
In this study a 3-factor, 3-level Box-Behnken design was used to prepare optimized docetaxel (DTX) loaded pegylated poly lactide-co-glycolide (PEG-PLGA) NPs with polymer concentration (X1), drug concentration (X2) and ratio of the organic to aqueous solvent (X3) as the independent variables and particle size (Y1), poly dispersity index (PDI) (Y2) and drug loading (Y3) as the responses. The cyto...
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ژورنال
عنوان ژورنال: BMC Cancer
سال: 2008
ISSN: 1471-2407
DOI: 10.1186/1471-2407-8-212