Pachyonychia congenita: New classification and diagnosis

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Pachyonychia Congenita: New Classification and Diagnosis

We would like to emphasize the importance of genetic testing to confirm a clinical diagnosis, draw your attention to the revised classification of pachyonychia congenita (PC) and provide further information regarding this rare skin disorder. Historically, PC was subdivided, with the two major clinical forms being PC-1 and PC-2. With an improvement in the understanding of the disease based on de...

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Pachyonychia Congenita: Brief Appraisal of History and Current Classification

287 Indian Dermatology Online Journal | Volume 8 | Issue 4 | July‐August 2017 Sir, We read with great interest the informative case report “Pachyonychia congenita with late onset (PC tarda)” by Sravanthi et al. in the July‐August 2016 issue of the Journal.[1] However, we would like to emphasize certain points regarding the history and current classification system of this rare disorder of kerat...

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Treatment of pachyonychia congenita.

There are currently no specific treatments for pachyonychia congenita (PC). Available treatments generally are directed at specific manifestations of the disorder, and an effective treatment plan must recognize that different patients are more or less troubled by different manifestations of the disease. Treatment for all aspects of PC has been less than completely satisfactory. Very few studies...

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Pachyonychia Congenita-Associated Alopecia

A 5-year-old female, known case of pachyonychia congenita, presented with diffuse hair loss; remaining hairs were easily plucked kinky hairs. Hair samples from patient were investigated using a light microscope. The hairs of the patients were mainly anagen hairs and unlike normal plucked anagen hairs, showed keratinization and cornification of their hair bulbs. No specific hair shaft abnormalit...

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Pachyonychia congenita Authors: Professors

Pachyonychia congenita (PC) is a rare genodermatosis affecting the nails and other ectodermal tissues. It is mainly characterized by gross thickening of all finger and toe nails. Different additional clinical features are observed; they fit into two major types: the Jadassohn-Lewandowsky and the Jackson-Lawler syndrome. The condition is usually transmitted as an autosomal dominant trait, though...

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ژورنال

عنوان ژورنال: Indian Journal of Dermatology

سال: 2016

ISSN: 0019-5154

DOI: 10.4103/0019-5154.190110