Pachydermoperiostosis (idiopathic hypertrophic osteoarthropathy)

[Pachydermoperiostosis (idiopathic hypertrophic osteoarthropathy)].

Introduction Pachydermoperiostosis is a syndrome characterized by finger clubbing, periosteal new bone formation especially over the distal ends of long bones, and coarsening of the facial features, with thickening, furrowing and oiliness of the skin of the face and forehead. The first reported cases were the Hagner brothers, who had typical features of this syndrome. They were first described ...

Pachydermoperiostosis (Primary Hypertrophic Osteoarthropathy): Case Report

syndrome consisting of clubbing of the digits of the hands and feet, enlargement of the extremities secondary to periarticular and osseous proliferation, and painful and swollen joints. The condition has been divided into two categories, primary hypertrophic osteoarthropathy, also known as “pachydermoperiostosis”, and secondary hypertrophic osteoarthropathy, frequently referred to as “hypertrop...

Pachydermoperiostosis (primary hypertrophic osteoarthropathy): report of a case with evidence of endothelial and connective tissue involvement.

A case of pachydermoperiostosis characterised by the presence of finger clubbing, periostosis, sweating of hands and feet is described. Modifications of capillaroscopic pattern and of arteriovenous anastomoses are reported. The periungual border and finger tip tissue showed diffuse endothelial hyperplasia, hyalinosis, and sclerosis with packing of collagen fibres. Electron microscopy showed hyp...

[Primary hypertrophic osteoarthropathy (pachydermoperiostosis). Report of two familial cases and literature review].

The primary hypertrophic osteoarthropathy (pachydermoperiostosis) is a hereditary disease characterized by skin thickening (pachydermia), finger clubbing, and proliferation of periosteum (periostitis) with subperiosteal new bone formation. We describe the cases of two brothers of 30 and 24 years, who consulted due to bone pain, arthralgia and oligoarthritis. Pachydermia, hyperhidrosis, seborrhe...

Can fibroblasts determine the late differing outcome between systemic sclerosis and primary hypertrophic osteoarthropathy (pachydermoperiostosis)?