P868 Dissecting myocardium

HYPOVENTILATION PRIOR TO ISCHEMIA PRECONDITIONS RAT MYOCARDIUM

Repetitive episodes of brief regional ischemia have been shown to reduce the severity of life-threatening ventricular anhythrnias and infarct size that occur during prolonged occlusion of the coronary artery. This phenomenon is known as ischemic preconditioning. During studies in anesthetized, open chest Wistar rats, we accidentally observed that poorly ventilated animals had a reduced seve...

Dissecting "deception".

“Dissecting Bioethics,” edited by Tuija Takala and Matti Häyry, welcomes contributions on the conceptual and theoretical dimensions of bioethics. The section is dedicated to the idea that words defined by bioethicists and others should not be allowed to imprison people’s actual concerns, emotions, and thoughts. Papers that expose the many meanings of a concept, describe the different readings o...

Dissecting darwinism.

J ohn Hunter, the acclaimed “father of scientifi c surgery,” understood human anatomy through a process of careful dissection. From 1750 to 1793, he revolutionized modern surgical anatomy through the dissection of thousands of human samples derived from fresh human cadavers, which came from fresh graves (1). He was credited with educating over 2000 surgeons globally based on the doctrine of obs...

Healed dissecting aneurysm.

Dissecting stress with transcriptomics

In our ever-changing environment, we are frequently exposed to uncontrollable, threatening social or physical stimuli that are perceived as stress. The brain rapidly mounts a stress response, by releasing neurotransmitters, hormones and peptides-stress mediators-that orchestrate organism-wide changes in an attempt to meet the challenges of the stressful situation. Despite the adaptive value of ...