P6053Increased alpha2B-adrenergic receptors gene expression in platelets from patients with not adequately controlled essential hypertension
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منابع مشابه
Evaluation of gene expression of three adrenergic receptors in infertile women with poor ovarian response, candidate for IVF
Background: Most studies show that 9 to 24% of people who are in in vitro fertilization (IVF) cycles are women who respond poorly to ovarian stimulation. Women with poor ovarian response (POR) are a group of infertile patients whose ovarian reserve, ovarian response to medication, and the quality of ovum are declining. Therefore, the number of female cycles, the number of fetuses from the oocyt...
متن کاملChronic alpha-1-adrenergic blockade increases sympathoneural but not adrenomedullary activity in patients with essential hypertension.
OBJECTIVE Doxazosin, a selective alpha1-adrenoceptor antagonist, lowers blood pressure by reducing peripheral vascular resistance without causing reflex tachycardia. To discover whether antihypertensive treatment with an alpha1-adrenoceptor blocker is accompanied by an increase in sympathoadrenomedullary activity, we studied plasma catecholamine kinetics before and during treatment with doxazos...
متن کاملPeripheral adrenergic receptors in hypertension.
Increased sympathoadrenal activity appears to play an important role in the development or maintenance of elevated blood pressure in hypertensive patients and various animal models of hypertension. Alterations of adrenergic receptor number or responsiveness might contribute to this increased activity. We therefore reviewed the data on adrenergic receptor alterations in hypertension with special...
متن کاملDifferential Gene Expression Profile in Essential Hypertension
Essential hypertension affects 20-30% of the population worldwide and contributes significantly to mortality and morbidity[1] from cerebrovascular diseases, myocardial infarction, congestive heart failure and renal insufficiency. Essential hypertension is a prevalent disorder that leads to significant morbidity and mortality. Essential hypertension is defined as chronically elevated arterial pr...
متن کاملRole of the alpha2B-adrenergic receptor in the development of salt-induced hypertension.
Salt sensitivity is a common trait in patients with essential hypertension and seems to have both an inherited and an acquired component (eg, is influenced by aging and renal insufficiency). Experimental evidence suggests that salt loading induces hypertension via a neurogenic mechanism mediated by the alpha2-adrenergic receptors (alpha2-AR). To explore the alpha2-AR subtype involved in this me...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2017
ISSN: 0195-668X,1522-9645
DOI: 10.1093/eurheartj/ehx493.p6053