p53 and FBXW7: Sometimes Two Guardians Are Worse than One

Cargo Transport: Two Motors Are Sometimes Better Than One

Molecular motor proteins are crucial for the proper distribution of organelles and vesicles in cells. Much of our current understanding of how motors function stems from studies of single motors moving cargos in vitro. More recently, however, there has been mounting evidence that the cooperation of multiple motors in moving cargos and the regulation of motor-filament affinity could be key mecha...

Many Minds are No Worse than One

When two obese parents are worse than one! Impacts on embryo and fetal development.

The prevalence of overweight and obesity in reproductive-age adults is increasing worldwide. While the effects of either paternal or maternal obesity on gamete health and subsequent fertility and pregnancy have been reported independently, the combination of having both parents overweight/obese on fecundity and offspring health has received minimal attention. Using a 2 × 2 study design in roden...

Binocular fusion of luminance, color, motion and flicker – Two eyes are worse than one

UNLABELLED How much information is conserved, or discarded, as it travels through the visual system? A target (an oriented bar) was defined by dark grey spots embedded in light spots for the left eye, and by light grey spots embedded in dark spots for the right eye. With one eye open, the target bars were clearly visible, but with both eyes open the light and dark spots fused binocularly into m...

When two heads are better than one and when they can be worse: The amplification hypothesis.

According to the self-consistency model (Koriat, 2012a), confidence judgments in the responses to 2-alternative forced-choice items are correlated with the consensuality of the responses rather than with their correctness: For consensually correct (CC) items, for which the majority response is correct, accuracy is higher for the correct answer than for the wrong answer, whereas for consensually...