P.4.d.005 Combining clomipramine and paroxetine for treatment-resistant obsessive compulsive disorder
نویسندگان
چکیده
منابع مشابه
Intravenous Clomipramine for Treatment-Resistant Obsessive-Compulsive Disorder
BACKGROUND This open trial was conducted to evaluate the effectiveness of intravenous clomipramine (CMI) in refractory obsessive-compulsive disorder (OCD). METHODS Thirty OCD poor responders to previous multiple trials of anti-obsessive medications were selected and admitted to the hospital. Severity of the illness and response to treatment were primarily assessed by the Yale-Brown Obsessive ...
متن کاملClomipramine in Resistant Obsessive Compulsive Disorder
Twelve subjects with a diagnosis of Obsessive Compulsive Disorder who had not shown response to amitryptiline and imipramine/behaviour therapy underwent a cross over double blind trial with clomipramine and nortryptiline. Subjects who had earlier not shown response to the other drugs did not show response to clomipramine. The implications of these findings for clinical management are discussed.
متن کاملIn-patient treatment for resistant obsessive-compulsive disorder.
Obsessive Compulsive Disorder is one of the increasing psychological disorders. If not detected early and treated properly, obsessive-compulsive disorder usually becomes an incapacitating illness adversely affecting almost all aspects of the patient's life. Outpatient behavioral and pharmacotherapies frequently fail. This is a report on a severe case of obsessive-compulsive disorder that was tr...
متن کاملIntravenous clomipramine for obsessive-compulsive disorder refractory to oral clomipramine: a placebo-controlled study.
BACKGROUND Uncontrolled reports suggest that intravenous clomipramine hydrochloride may be effective for patients with obsessive-compulsive disorder (OCD) who are nonresponsive to oral clomipramine. METHODS Fifty-four patients with oral clomipramine-refractory OCD were randomized to receive 14 infusions of either placebo or clomipramine hydrochloride, starting at 25 mg/d and increasing to 250...
متن کاملOlanzapine augmentation of paroxetine-refractory obsessive-compulsive disorder.
The aim of the present study was to investigate the effect of adjunctive olanzapine in patients with obsessive-compulsive disorder (OCD) refractory to paroxetine. Twenty-one patients unresponsive to treatment with paroxetine, administered for at least 12 weeks at the dose of 60 mg/day, participated to a 12-week open-label, add-on trial with olanzapine (10 mg/day). The psychopathological state w...
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ژورنال
عنوان ژورنال: European Neuropsychopharmacology
سال: 2015
ISSN: 0924-977X
DOI: 10.1016/s0924-977x(15)30797-5