P450 Ustekinumab and vedolizumab for extraintestinal manifestations in inflammatory bowel disease

Extraintestinal Manifestations Associated with Inflammatory Bowel Disease.

Inflammatory bowel disease (IBD) affects multiple organ systems outside of the gastrointestinal tract. The clinician treating patients with IBD should be acutely aware of the diagnosis and treatment of extraintestinal manifestations in order to decrease morbidity. The management can be difficult and often times requires a multidisciplinary approach. Future research investigating the pathophysio...

Extraintestinal manifestations of inflammatory bowel disease.

Inflammatory bowel disease (IBD) is associated with a variety of extraintestinal manifestations (EIMs) that may produce greater morbidity than the underlying intestinal disease and may even be the initial presenting symptoms of the IBD. As many as 36% of patients with IBD have at least one EIM. Some are more common related to active colitis (joint, skin, ocular, and oral manifestations). Others...

Extraintestinal Manifestations of Inflammatory Bowel Disease

Extraintestinal Manifestations of Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) mainly affects the gastrointestinal system but is associated with various chronic diseases of other organs that are jointly called extraintestinal manifestations (EIM). In some of these disorders, onset and clinical manifestations are associated with the course of the intestinal disease while in others they are independent of the intestinal disease. The former i...

Extraintestinal Manifestations of Inflammatory Bowel Disease

Extraintestinal manifestations (EIM) in inflammatory bowel disease (IBD) are frequent and may occur before or after IBD diagnosis. EIM may impact the quality of life for patients with IBD significantly requiring specific treatment depending on the affected organ(s). They most frequently affect joints, skin, or eyes, but can also less frequently involve other organs such as liver, lungs, or panc...