P183 Development of a new simple ultrasound activity score for intestinal Behçet's Disease

Abstract Background Intestinal Behçet's disease (BD) is a relapsing-remitting typically associated with punched-out ulcers in the ileocecal region. Optimal monitoring of activity necessary; however, ileocolonoscopy cannot be performed on regular basis as it invasive, resource-intensive and causes considerable patient discomfort. Furthermore, there are risks intestinal bleeding perforation caused by pretreatment laxatives air insufflation during examination. Hence, other follow-up examinations required. ultrasonography (IUS) minimally invasive imaging method, but no previous reports comparisons between IUS endoscopy for BD. This study aimed to evaluate usefulness assessing Methods retrospective single-centre included patients BD who underwent colonoscopy within 2 weeks, from 2007 2020. Correlations corresponding endoscopic using Sakita–Miwa classification six variables (bowel wall thickness [BWT], vascularity, bowel stratification, intramural extramural abscesses, fistulas mesenteric lymphadenopathy) were assessed used select that should new simple score. findings also compared biomarker (C-reactive protein [CRP]) concentrations clinical severity indices (Crohn’s index [DAIBD]). Results Seventy-nine 53 included. Univariate analysis revealed CRP DAIBD BWT, vascularity stratification abscesses differed significantly according ulcer activity. Multivariate logistic regression model only BWT statistically different; therefore, score ([2*BWT] + [5*vascularity]) was constructed. Receiver operating characteristic curve an area under 0.91 detecting activity, which superior those (0.80; P=0.069), Crohn’s (0.69; P=0.002) (0.67; P<0.001). Conclusion A ultrasound comprising constructed correlated well first report describing BD, we believe will have many implications practice.