P163 Is Peri-appendiceal Inflammation of Clinical Significance in Patients with Ulcerative Colitis?

Abstract Background Peri-appendiceal inflammation (PAI) is often found in patients with left-sided ulcerative colitis (UC) or proctitis. However, there still no consensus on the clinical significance of PAI. This study aimed to identify PAI UC as a prognosis factor. Methods We retrospectively collected medical records and endoscopic results diagnosed left side proctitis between January 2013 December 2021. According presence PAI, we divided into non-PAI groups. Demographic features course two groups were analyzed. Results A total 107 (41 site UC, 56 proctitis) enrolled, which 52 group 55 There was difference most demographic variables During follow-up period 51 months for 46 group, respectively, disease relapse rate (47.1% vs 49.1%, p=0.823), cumulative at 1, 3, 5 years (10.7%, 26.2%, 34.8% 8.39%, 23.0%, 36.7%, treatment escalation (59.6% 41.8%, p=0.066) proximal extension (25% 25.5%, p=0.957) however, new occurrence during associated (55.6% 19.6%, p=0.037) In this study, oral 5-aminosalicylate (ASA) administered regardless extent disease. 5-ASA did not affect (37.1% 66.7%, p=0.550) (28.6% 33.3%, p=1.000). Conclusion diagnosis nor proctitis, however occurrences extension.