P06 Stewardship potential—the hidden burden of antibiotic prophylaxis in primary care

Abstract Background This study aimed to decrease unnecessary long-term antimicrobial use in primary care by identifying and highlighting patients with or repeated exposure antibiotics GP teams for review. The broad spectrum co-amoxiclav was targeted following data showing rising DDD per prescription our Health Board. Methods Community antibiotic prescribing from the national Prescribing Information System (PIS) searched NHS Lothian (126 practices) using identify patients. Long courses of were defined as ≥63 DDD. Ninety-eight identified high usage a collection form sent Primary Care Pharmacy voluntarily collate each patient. Results had 97% response rate. Of 94 full 62 (66%) initiated due secondary specialist advice 26 (28%) been care. Forty-four (47%) aged 65 over, putting them at risk Clostridioides difficile. Forty-one multiple 39 prescribed prophylaxis; these 59% urinary tract infection (UTI). Thirty-four (36%) on prophylaxis over 5 years 9 20 years. note no microbiology samples available where (n=55), narrower options 38 (69%) 17 (31%) resistance co-amoxiclav. Following this intervention highlight use, number reduced 70% year. Conclusions Patients are priorities stewardship interventions. work demonstrated that ongoing appropriateness efficacy not routinely reviewed. Using pharmacy proved an effective method ultimately reduce patient exposure. UTI majority group interventions review Board underway.