P027 Enhanced luminal alkalization and increased epithelial permeability in TNF-α overexpressing murine proximal colon
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چکیده
منابع مشابه
Regulation of P-Glycoprotein in Renal Proximal Tubule Epithelial Cells by LPS and TNF-α
During endotoxemia, the ATP-dependent drug efflux pump P-glycoprotein (Abcb1/P-gp) is upregulated in kidney proximal tubule epithelial cells. The signaling pathway through which lipopolysaccharide (LPS) or tumor necrosis factor-alpha (TNF-alpha) regulates P-gp expression and activity was investigated further in the present study. Exposure of rat kidney proximal tubule cells to TNF-alpha alone o...
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ژورنال
عنوان ژورنال: Journal of Crohn's and Colitis
سال: 2012
ISSN: 1873-9946
DOI: 10.1016/s1873-9946(12)60048-8