منابع مشابه
A 24-week open-label extension study of memantine in moderate to severe Alzheimer disease.
BACKGROUND This study is an extension of a 28-week, randomized, double-blind, placebo-controlled study of memantine in 252 patients with moderate to severe Alzheimer disease. OBJECTIVE To evaluate long-term memantine treatment in moderate to severe Alzheimer disease. DESIGN, SETTING, AND PATIENTS Open-label, 24-week extension trial. Raters remained blind to the patients' initial study treat...
متن کاملSafety and tolerability of the rivastigmine patch: results of a 28-week open-label extension.
The primary objective of the open-label extension was to evaluate the long-term safety and tolerability of a transdermal rivastigmine patch up to 1 year, as a novel approach to treatment in Alzheimer disease. This was a 28-week extension to a 24-week, double-blind, double-dummy, placebo-controlled, and active-controlled study evaluating rivastigmine patches [9.5 mg/24 h (10 cm2) and 17.4 mg/24 ...
متن کاملLurasidone in the Long‐term Treatment of Patients with Bipolar Disorder: a 24‐week Open‐label Extension Study
BACKGROUND The aim of this study was to evaluate the safety and tolerability of 6 months of open-label, uncontrolled extension treatment with lurasidone in patients with a diagnosis of bipolar depression who completed 6 weeks of acute treatment. METHODS Patients completing 6 weeks of double-blind placebo-controlled treatment with either lurasidone monotherapy (one study) or adjunctive therapy...
متن کاملConsent to open label extension studies: some ethical issues.
A frequent feature of pharmaceutical research is the open label extension study, in which patients participating in double blind placebo controlled trials of new medications are invited, on completion of the initial trial, to take the study drug for some further period. Patients are openly given the active substance at this stage, regardless of their assignment in the initial trial. Investigato...
متن کاملWelcome to Nursing Open
I am pleased to announce the launch of Nursing Open, a peer-reviewed, international, fully open access journal that welcomes articles on all aspects of nursing and midwifery practice, research, education and policy. You have probably lost track of the number of open access nursing journals but you cannot have failed to notice the daily onslaught of invitations to submit to, edit or join the edi...
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ژورنال
عنوان ژورنال: Inflammatory Bowel Diseases
سال: 2014
ISSN: 1078-0998
DOI: 10.1097/01.mib.0000442971.65229.5b