P-051 Male cancer patient sperm cryopreservation for fertility preservation: 11-year multicenter experience: 16 regions of the mainland China national sperm

Abstract Study question What is the current status of fertility preservation (FP) male cancer utilization, efficacy and safety in China what national trends could be observed? Summary answer In this report on FP over a 11-year period, data population trends, region development are analyzed. known already Cryopreservation sperm, standard option to preserve patient's fertility, very advantageous for men suffering from cancer. Unfortunately, (FP)of mainland scarce. design, size, duration A multicenter retrospective study patients who performed sperm cryopreservation 16 regions network banks period 2010 2020. total 2270 with were referred human preservation. Participants/materials, setting, methods This survey was conducted through provincial administrative sectors Chinese Sperm banks, which done well Cancer diagnoses classified according types, as Testicular tumors, Lymphomas, Leukemia, Colorectal Nasopharyngeal carcinomas, Sarcomas, Brain Extragonadal germ cell other cancers grouped together. Main results role chance The number showed an overall upward trend. Statistically significant mean yearly increases observed three most frequent types (testicular cancers, lymphoma, leukemia). eastern, central, western displayed imbalance. There seven tumor top incidence ten including leukemia, nasopharyngeal carcinoma, sarcoma, thyroid brain tumor. Moreover, carcinoma high rate China, related rate, different others countries. percentage males receiving testicular (15-39 years old) 2020 5.55%, 1.29% lymphoma 0.39% Leukemia. According type cancer, statistically lower pre-sperm density, output post-sperm density cancers. It's worth noting that prevalence azoospermia 22.2 % Leukemia patients. Disposition cryopreserved categories included continued storage (47.2%), discarded (9%), death (0.9%), use (3.7%). Up 2020, 70 (3.7%) underwent assisted reproductive technology (ART) used their semen. Limitations, reasons caution limitations our inability follow-up couples naturally conceived. Another limitation not all clinical outcomes have been gated. Wider implications findings provides comprehensive statistical census review quantity types. Our regarding patients’ characteristics analysis semen parameters usage rate. Trial registration applicable