Oxygen versus Reactive Oxygen in the Regulation of HIF-1α: The Balance Tips
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منابع مشابه
Oxygen versus Reactive Oxygen in the Regulation of HIF-1α: The Balance Tips
Hypoxia inducible factor (HIF) is known as the master regulator of the cellular response to hypoxia and is of pivotal importance during development as well as in human disease, particularly in cancer. It is composed of a constitutively expressed β subunit (HIF-1β) and an oxygen-regulated α subunit (HIF-1α and HIF-2α), whose stability is tightly controlled by a family of oxygen- and iron-depende...
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ژورنال
عنوان ژورنال: Biochemistry Research International
سال: 2012
ISSN: 2090-2247,2090-2255
DOI: 10.1155/2012/436981