Oxygen saturation monitoring using resonance Raman spectroscopy

Hemoglobin oxygen saturation measurements using resonance Raman intravital microscopy.

A system is described for in vivo noninvasive measurements of hemoglobin oxygen saturation (HbO2Sat) at the microscopic level. The spectroscopic basis for the application is resonant Raman enhancement of Hb in the violet/ultraviolet region, allowing simultaneous identification of oxy- and deoxyhemoglobin with the same excitation wavelength. The heme vibrational bands are well known, but the tec...

Tissue oxygenation monitoring using resonance Raman spectroscopy during hemorrhage.

BACKGROUND The ability to monitor the patient of hemorrhage noninvasively remains a challenge. We examined the ability of resonance Raman spectroscopy to monitor tissue hemoglobin oxygenation (RRS-StO2) during hemorrhage and compared its performance with conventional invasive mixed venous (SmvO2) and central venous (ScvO2) hemoglobin oxygen saturation as well as with near-infrared spectroscopy ...

Innovative Methodology Hemoglobin oxygen saturation measurements using resonance Raman intravital microscopy

Torres Filho, Ivo P., James Terner, Roland N. Pittman, Leonardo G. Somera III, and Kevin R. Ward. Hemoglobin oxygen saturation measurements using resonance Raman intravital microscopy. Am J Physiol Heart Circ Physiol 289: H488–H495, 2005. First published March 11, 2005; doi:10.1152/ajpheart.01171.2004.—A system is described for in vivo noninvasive measurements of hemoglobin oxygen saturation (H...

Monitoring tissue blood oxygen saturation in the internal jugular venous area using near infrared spectroscopy.

Central venous blood oxygen saturation (ScvO2) is an important monitoring index of fluid resuscitation. However, monitoring of ScvO2 is not continuous and invasive. Near infrared spectroscopy (NIRS) is an optical technology for the noninvasive detection of hemodynamic changes, with advantages of being real-time, continuous, low-cost, and portable. The present study aimed to determine whether a ...

2.1 Resonance Raman spectroscopy…………………………………………………..10