Oxygen-dependent Radiosensitivity ofEscherichia coliand Mitigation in Lethality by Super oxide Dismutase

Treatment of super oxide dismutase assay by a regression method

Cadherin-dependent cell aggregation is affected by decapeptide derived from rat extracellular super-oxide dismutase.

A synthetic HAV-containing decapeptide homologous to the amino acid sequence 44R-Q53 in rat extracellular superoxide dismutase B affects cadherin-dependent cell aggregation. Cell lines, some of them transfected, expressing different types of cadherins were tested using in vitro cell aggregation and cell dissociation assays. A concentration-dependent inhibition of aggregation by the EC-SOD-deriv...

Preparation and Characterization of Pulmonary Surfactant- Super Oxide Dismutase Liposomes

Objective: To prepare pulmonary surfactant-superoxide dismutase (PS-SOD) Liposomes and analyze the biological characteristics of them. Methods: To prepare PS-SOD Liposomes with rotary evaporation method and analyze the formulation and bioactivity of them, including shape, size, encapsulating ratio, antioxidant activity and surface tension. Results: The PS-SOD Liposome is a kind of ivory white s...

Oxygen-dependent mutagenesis in Escherichia coli lacking superoxide dismutase.

Escherichia coli double mutants (sodA sodB) completely lacking superoxide dismutase (SOD) have greatly enhanced mutation rates during aerobic growth. Single mutants lacking manganese SOD (MnSOD) but possessing iron SOD (FeSOD) have a smaller increase, and single mutants lacking FeSOD but possessing MnSOD do not show such an increase. The enhancement of mutagenesis is completely dependent on the...

Oxygen-dependent reversible inhibition of mitochondrial respiration by nitric oxide.

Effects of nitric oxide (NO) and NO generating agents, on the electron transport system of mitochondria were examined in a study of the mechanism and physiological importance of NO in energy metabolism. In the presence of various substrates, uncoupled respiration was inhibited by NO in manner which was both dose- and oxygen tension-dependent. Simultaneously measuring changes in cytochrome absor...