Oxybutynin and its New Transdermal Application for the Treatment of Overactive Bladder
نویسندگان
چکیده
منابع مشابه
Transdermal oxybutynin in the treatment of overactive bladder
Overactive bladder is a dreadful syndrome that affects a considerable number of patients. Antimuscarinics are the mainstay of pharmacotherapy for this condition. Transdermal (TD) oxybutynin (OXY) bypasses the first-pass metabolism and reduces the formation of N-desethyloxybutynin, a compound believed to be associated with anticholinergic side effects. The 3.9 mg matrix TD system is applied twic...
متن کاملTransdermal drug delivery treatment for overactive bladder.
Overactive bladder is commonly treated with oral anticholinergic drugs such as oxybutynin chloride. Although oral anticholinergic agents have been effective in controlling urinary urgency and incontinence, adverse events, particularly dry mouth, often cause patients to discontinue oral therapy and to endure incontinence. Oxybutynin can be delivered transcutaneously, maintaining the efficacy of ...
متن کاملOxybutynin topical gel in the treatment of overactive bladder
Overactive bladder (OAB), often accompanied by urinary incontinence, is most prevalent among the elderly, but also affects many middle-aged men and women in the US. OAB may severely impair quality of life, and its overall economic costs to society are substantial. Although antimuscarinic agents relieve OAB symptoms effectively, treatment persistence generally is low. This has been attributed in...
متن کاملPatient perspectives in the management of overactive bladder, focus on transdermal oxybutynin
Overactive bladder syndrome (OAB) is a constellation of distressing symptoms that significantly impair quality of life, sexual function, and work productivity, and imposes a significant economic burden to society. Pharmacological treatment with antimuscarinic agents, behavioral modification, bladder retraining, and/or pelvic floor exercises are often used alone or in combination as the mainstay...
متن کاملoxybutynin and tolterodine in a trial for treatment of overactive bladder in iranian women.
objective: to evaluate the efficacy and side effects of oxybutinin in comparison to tolterodine in treatment of overactive bladder (oab) with detrussor overactivity (doa) in iranian women. materials and methods: one hundred iranian old women with clinical symptoms of oab who show ido in the filling cystometry participated in this randomized double-blinded parallel-group by using two kinds of th...
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ژورنال
عنوان ژورنال: Women's Health
سال: 2006
ISSN: 1745-5065,1745-5065
DOI: 10.2217/17455057.2.2.225