Oxidative stress induced chondrocytes apoptosis were inhibited by eicosapentaenoic acid
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چکیده
منابع مشابه
Oxidative stress-induced apoptosis and matrix loss of chondrocytes is inhibited by eicosapentaenoic acid.
Eicosapentaenoic acid (EPA) is an antioxidant and n-3 polyunsaturated fatty acid that reduces the production of inflammatory cytokines. We evaluated the role of EPA in chondrocyte apoptosis and degeneration. Normal human chondrocytes were treated with EPA and sodium nitroprusside (SNP). Expression of metalloproteinases (MMPs) was detected by real-time polymerase chain reaction (PCR) and that of...
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2013
ISSN: 1063-4584
DOI: 10.1016/j.joca.2013.02.095