Oxidative Stress and the Central Nervous System
نویسندگان
چکیده
منابع مشابه
Oxidative Stress and the Central Nervous System.
Biochemical integrity of the brain is vital for normal functioning of the central nervous system (CNS). One of the factors contributing to cerebral biochemical impairment is a chemical process called oxidative stress. Oxidative stress occurs upon excessive free radical production resulting from an insufficiency of the counteracting antioxidant response system. The brain, with its high oxygen co...
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Oxidative stress is associated with the onset and pathogenesis of several prominent central nervous system disorders. Consequently, there is a pressing need for experimental methods for studying neuronal responses to oxidative stress. A number of techniques for modeling oxidative stress have been developed, including the use of inhibitors of the mitochondrial respiratory chain, depletion of end...
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Constantly growing body of evidence suggests that hallmarks of oxidative stress are present in various central nervous system (CNS) disorders. Technological advantages in cell culturing made it possible to use neural cell/tissue cultures as experimental models for investigation of molecular mechanisms which underlie the development of oxidative stress condition, damage and adaptive responses to...
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ژورنال
عنوان ژورنال: Journal of Pharmacology and Experimental Therapeutics
سال: 2016
ISSN: 0022-3565,1521-0103
DOI: 10.1124/jpet.116.237503