منابع مشابه
Oxidant gases.
The acute and chronic action of the oxidant gases ozone, nitrogen dioxide and oxygen on the morphological appearance of cells of the alveolar and bronchiolar epithelium is reviewed. Type I cells of the alveolar and ciliated cells of the bronchiolar epithelium appear to be sensitive targets for the oxidant gases. The degree of damage is influenced by age, nutritional status and the development o...
متن کاملExposing animals to oxidant gases: nose only vs. whole body.
Inhalation experiments using laboratory animals are performed under controlled conditions to assess the toxicity of and to investigate interventional strategies to ameliorate injury resulting from oxidant gas exposures. A variety of dynamic inhalation exposure systems that use whole-body or nose-only exposure chambers have been developed for rodents. In a whole-body exposure chamber, the animal...
متن کاملRisk assessment of oxidant gases and particulate air pollutants: uncertainties and research needs.
The assessment of risks to human health associated with exposure to oxidant air pollutants has not received adequate attention despite the recognized public health threat posed by the ubiquitous presence of these compounds in the environment. In this article, research needs and uncertainties at each of the steps in the risk assessment of oxidant air pollutants are identified: hazard identificat...
متن کاملOxidant anti-oxidant imbalance and effects of ethanol.
This article discusses some of the mechanisms through which alcohol, delivered pre- or postnatally, alters the activity of the rodent hypothalamic-pituitary-adrenal (HPA) axis. We show that blockade of prostaglandin synthesis, but not opiate receptors, modestly interfered with the HPA axis to acute alcohol injection. Pretreatment with a low dose of alcohol (0.3 g/kg) did not significantly modif...
متن کاملOxidant stress in asthma.
Asthma is a chronic inflammatory disease of the respiratory tract of unknown aetiology. In severe asthma airway diathesis is profound, and thus apparent. Recently, however, evidence has indicated that specific inflammatory abnormalities exist even in the airways of subjects with mild disease. As inflammation is often associated with an increased generation of reactive oxygen species (ROS), and ...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1984
ISSN: 0091-6765
DOI: 10.2307/3429694