Oxalate Quantification in Hemodialysate to Assess Dialysis Adequacy for Primary Hyperoxaluria
نویسندگان
چکیده
منابع مشابه
Sequential studies of oxalate dynamics in primary hyperoxaluria.
We have measured the total plasma clearance, renal clearance and equilibrium distribution volume of [14C]oxalate, and the urinary oxalate excretion rate and plasma oxalate levels at approximately 6 months intervals for up to 2.5 years in five patients with primary hyperoxaluria. The renal clearance and distribution volumes of [99mTc]DTPA (diethylenetriaminepenta-acetate) were measured simultane...
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BACKGROUND Primary hyperoxaluria (PH) is a rare genetic disease, in which high urinary oxalate (Uox) cause recurrent kidney stones and/or progressive nephrocalcinosis, often followed by early end-stage renal disease, as well as extremely high plasma oxalate, systemic oxalosis and premature death. Oxalobacter formigenes, an anaerobic oxalate degrading bacterium, naturally colonizes the colon of ...
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متن کاملPrimary Hyperoxaluria
Primary hyperoxalurias are rare recessive inherited inborn errors of glyoxylate metabolism. They are responsible for progressive renal involvement, which further lead to systemic oxalate deposition, which can even occur in infants. Primary hyperoxaluria type 1 is the most common form in Europe and is due to alanine-glyoxylate aminostransferase deficiency, a hepatic peroxisomal pyridoxin-depende...
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ژورنال
عنوان ژورنال: American Journal of Nephrology
سال: 2014
ISSN: 0250-8095,1421-9670
DOI: 10.1159/000360624